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Dysbacteriosis-Derived Lipopolysaccharide Causes Embryonic Osteopenia through Retinoic-Acid-Regulated DLX5 Expression

Growing evidence suggests an adverse impact of gut microbiota dysbiosis on human health. However, it remains unclear whether embryonic osteogenesis is affected by maternal gut dysbacteriosis. In this study, we observed that elevated lipopolysaccharide (LPS) levels led to skeletal developmental retar...

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Detalles Bibliográficos
Autores principales: You, Lingsen, Zhu, Liwei, Li, Pei-zhi, Wang, Guang, Cai, Hongmei, Song, Jinhuan, Long, Denglu, Berman, Zachary, Lin, Li, Cheng, Xin, Yang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177785/
https://www.ncbi.nlm.nih.gov/pubmed/32260461
http://dx.doi.org/10.3390/ijms21072518