The Tumor Suppressor TFF1 Occurs in Different Forms and Interacts with Multiple Partners in the Human Gastric Mucus Barrier: Indications for Diverse Protective Functions

TFF1 is a protective peptide of the Trefoil Factor Family (TFF), which is co-secreted with the mucin MUC5AC, gastrokine 2 (GKN2), and IgG Fc binding protein (FCGBP) from gastric surface mucous cells. Tff1-deficient mice obligatorily develop antropyloric adenoma and about 30% progress to carcinomas,...

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Detalles Bibliográficos
Autores principales: Heuer, Jörn, Heuer, Franziska, Stürmer, René, Harder, Sönke, Schlüter, Hartmut, Braga Emidio, Nayara, Muttenthaler, Markus, Jechorek, Dörthe, Meyer, Frank, Hoffmann, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177788/
https://www.ncbi.nlm.nih.gov/pubmed/32260357
http://dx.doi.org/10.3390/ijms21072508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177788/
https://www.ncbi.nlm.nih.gov/pubmed/32260357
http://dx.doi.org/10.3390/ijms21072508

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