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The ULK1/2 and AMPK Inhibitor SBI-0206965 Blocks AICAR and Insulin-Stimulated Glucose Transport

The small molecule kinase inhibitor SBI-0206965 was originally described as a specific inhibitor of ULK1/2. More recently, it was reported to effectively inhibit AMPK and several studies now report its use as an AMPK inhibitor. Currently, we investigated the specificity of SBI-0206965 in incubated m...

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Detalles Bibliográficos
Autores principales: Knudsen, Jonas R., Madsen, Agnete B., Persson, Kaspar W., Henríquez-Olguín, Carlos, Li, Zhencheng, Jensen, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177789/
https://www.ncbi.nlm.nih.gov/pubmed/32231045
http://dx.doi.org/10.3390/ijms21072344