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Detecting the Effects of the Glucocorticoid Dexamethasone on Primary Human Skeletal Muscle Cells—Differences to the Murine Cell Line

Skeletal muscle atrophy is characterized by a decrease in muscle fiber size as a result of a decreased protein synthesis, which leads to degradation of contractile muscle fibers. It can occur after denervation and immobilization, and glucocorticoids (GCs) may also increase protein breakdown contribu...

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Detalles Bibliográficos
Autores principales: Langendorf, Eva K., Rommens, Pol M., Drees, Philipp, Mattyasovszky, Stefan G., Ritz, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177793/
https://www.ncbi.nlm.nih.gov/pubmed/32260276
http://dx.doi.org/10.3390/ijms21072497