Glyceraldehyde-Derived Pyridinium Evokes Renal Tubular Cell Damage via RAGE Interaction

Glyceraldehyde-derived advanced glycation end products (glycer-AGEs) contribute to proximal tubulopathy in diabetes. However, what glycer-AGE structure could evoke tubular cell damage remains unknown. We first examined if deleterious effects of glycer-AGEs on reactive oxygen species (ROS) generation...

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Detalles Bibliográficos
Autores principales: Sotokawauchi, Ami, Nakamura, Nobutaka, Matsui, Takanori, Higashimoto, Yuichiro, Yamagishi, Sho-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177832/
https://www.ncbi.nlm.nih.gov/pubmed/32283652
http://dx.doi.org/10.3390/ijms21072604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177832/
https://www.ncbi.nlm.nih.gov/pubmed/32283652
http://dx.doi.org/10.3390/ijms21072604

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