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Glyceraldehyde-Derived Pyridinium Evokes Renal Tubular Cell Damage via RAGE Interaction

Glyceraldehyde-derived advanced glycation end products (glycer-AGEs) contribute to proximal tubulopathy in diabetes. However, what glycer-AGE structure could evoke tubular cell damage remains unknown. We first examined if deleterious effects of glycer-AGEs on reactive oxygen species (ROS) generation...

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Detalles Bibliográficos
Autores principales:	Sotokawauchi, Ami, Nakamura, Nobutaka, Matsui, Takanori, Higashimoto, Yuichiro, Yamagishi, Sho-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177832/ https://www.ncbi.nlm.nih.gov/pubmed/32283652 http://dx.doi.org/10.3390/ijms21072604

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