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2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic pathogen responsible for many hospital-acquired infections. P. aeruginosa can thrive in diverse infection scenarios by rewiring its central metabolism. An example of this is the production of biomass from C(2) nutrient sources such as acetate via the glyoxy...

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Detalles Bibliográficos
Autores principales: McVey, Alyssa C., Bartlett, Sean, Kajbaf, Mahmud, Pellacani, Annalisa, Gatta, Viviana, Tammela, Päivi, Spring, David R., Welch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177833/
https://www.ncbi.nlm.nih.gov/pubmed/32260167
http://dx.doi.org/10.3390/ijms21072490