Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967

Many epilepsy patients are refractory to conventional antiepileptic drugs. Resurgent and persistent currents can be enhanced by epilepsy mutations in the Nav1.2 channel, but conventional antiepileptic drugs inhibit normal transient currents through these channels, along with aberrant resurgent and p...

Descripción completa

Detalles Bibliográficos
Autores principales: Mason, Emily R., Cummins, Theodore R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177867/
https://www.ncbi.nlm.nih.gov/pubmed/32244818
http://dx.doi.org/10.3390/ijms21072454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177867/
https://www.ncbi.nlm.nih.gov/pubmed/32244818
http://dx.doi.org/10.3390/ijms21072454

Ejemplares similares