Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and Neurodegeneration

Still unresolved is the question of how a lifetime accumulation of somatic gene copy number alterations impact organ functionality and aging and age-related pathologies. Such an issue appears particularly relevant in the broadly post-mitotic central nervous system (CNS), where non-replicative neuron...

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Detalles Bibliográficos
Autores principales: Ain, Quratul, Schmeer, Christian, Wengerodt, Diane, Witte, Otto W., Kretz, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177960/
https://www.ncbi.nlm.nih.gov/pubmed/32252492
http://dx.doi.org/10.3390/ijms21072477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177960/
https://www.ncbi.nlm.nih.gov/pubmed/32252492
http://dx.doi.org/10.3390/ijms21072477

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