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Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and Neurodegeneration
Still unresolved is the question of how a lifetime accumulation of somatic gene copy number alterations impact organ functionality and aging and age-related pathologies. Such an issue appears particularly relevant in the broadly post-mitotic central nervous system (CNS), where non-replicative neuron...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177960/ https://www.ncbi.nlm.nih.gov/pubmed/32252492 http://dx.doi.org/10.3390/ijms21072477 |