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Stomatin-like Protein 2 Promotes Tumor Cell Survival by Activating the JAK2-STAT3-PIM1 Pathway, Suggesting a Novel Therapy in CRC

Despite intensive efforts, a considerable proportion of colorectal cancer (CRC) patients develop local recurrence and distant metastasis. Stomatin-like protein 2 (SLP-2), a member of the highly conserved stomatin superfamily, is upregulated across cancer types. However, the biological and functional...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Li, Anqi, Wang, Lisha, He, Wei, Zhao, Ling, Wu, Chao, Lu, Shasha, Ye, Xuanguang, Zhao, Huiyong, Shen, Xiaohan, Xiao, Xiuying, Liu, Zebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177985/
https://www.ncbi.nlm.nih.gov/pubmed/32346607
http://dx.doi.org/10.1016/j.omto.2020.03.010