Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias

Ryanodine receptor 2 (RyR2) and SERCA2a are two major players in myocyte calcium (Ca) cycling that are modulated physiologically, affected by disease and thus considered to be potential targets for cardiac disease therapy. However, how RyR2 and SERCA2a influence each others’ activities, as well as t...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Bin, Lou, Qing, Smith, Heather, Velez-Cortes, Florencia, Dillmann, Wolfgang H., Knollmann, Björn C., Armoundas, Antonis A., Györke, Sándor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178036/
https://www.ncbi.nlm.nih.gov/pubmed/32260593
http://dx.doi.org/10.3390/ijms21072535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178036/
https://www.ncbi.nlm.nih.gov/pubmed/32260593
http://dx.doi.org/10.3390/ijms21072535

Ejemplares similares