Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease

Gangliosidoses are caused by monogenic defects of a specific hydrolase or an ancillary sphingolipid activator protein essential for a specific step in the catabolism of gangliosides. Such defects in lysosomal function cause a primary accumulation of multiple undegradable gangliosides and glycosphing...

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Detalles Bibliográficos
Autores principales: Breiden, Bernadette, Sandhoff, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178057/
https://www.ncbi.nlm.nih.gov/pubmed/32272755
http://dx.doi.org/10.3390/ijms21072566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178057/
https://www.ncbi.nlm.nih.gov/pubmed/32272755
http://dx.doi.org/10.3390/ijms21072566

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