Cargando…
Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease
Gangliosidoses are caused by monogenic defects of a specific hydrolase or an ancillary sphingolipid activator protein essential for a specific step in the catabolism of gangliosides. Such defects in lysosomal function cause a primary accumulation of multiple undegradable gangliosides and glycosphing...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178057/ https://www.ncbi.nlm.nih.gov/pubmed/32272755 http://dx.doi.org/10.3390/ijms21072566 |