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Biophysical Techniques for Target Validation and Drug Discovery in Transcription-Targeted Therapy

In the post-genome era, pathologies become associated with specific gene expression profiles and defined molecular lesions can be identified. The traditional therapeutic strategy is to block the identified aberrant biochemical activity. However, an attractive alternative could aim at antagonizing ke...

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Detalles Bibliográficos
Autores principales: Moustaqil, Mehdi, Gambin, Yann, Sierecki, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178067/
https://www.ncbi.nlm.nih.gov/pubmed/32225120
http://dx.doi.org/10.3390/ijms21072301