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Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation

Chronic high-glucose exposure results in the production of advanced glycation end-products (AGEs) leading to reactive oxygen species (ROS) generation, which contributes to the development of diabetic cardiomyopathy. PKCδ activation leading to ROS production and mitochondrial dysfunction involved in...

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Detalles Bibliográficos
Autores principales: Hsieh, Dennis Jine-Yuan, Ng, Shang-Chuan, Zeng, Ren-You, Padma, Viswanadha Vijaya, Huang, Chih-Yang, Kuo, Wei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178155/
https://www.ncbi.nlm.nih.gov/pubmed/32283691
http://dx.doi.org/10.3390/ijms21072608