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Diallyl Trisulfide (DATS) Suppresses AGE-Induced Cardiomyocyte Apoptosis by Targeting ROS-Mediated PKCδ Activation
Chronic high-glucose exposure results in the production of advanced glycation end-products (AGEs) leading to reactive oxygen species (ROS) generation, which contributes to the development of diabetic cardiomyopathy. PKCδ activation leading to ROS production and mitochondrial dysfunction involved in...
Autores principales: | Hsieh, Dennis Jine-Yuan, Ng, Shang-Chuan, Zeng, Ren-You, Padma, Viswanadha Vijaya, Huang, Chih-Yang, Kuo, Wei-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178155/ https://www.ncbi.nlm.nih.gov/pubmed/32283691 http://dx.doi.org/10.3390/ijms21072608 |
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