Differential Targeting of Gr-MDSCs, T Cells and Prostate Cancer Cells by Dactolisib and Dasatinib

Granulocytic myeloid-derived suppressor cells (Gr-MDSCs) promote immune evasion and resistance to immunotherapeutics in a variety of malignancies. Our previous study showed that dual PI3K/mTOR inhibitor Dactolisib impaired the viability and immunosuppressive function of Gr-MDSCs, and significantly s...

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Detalles Bibliográficos
Autores principales: Liu, Guoqiang, Jin, Zhijian, Lu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178187/
https://www.ncbi.nlm.nih.gov/pubmed/32230980
http://dx.doi.org/10.3390/ijms21072337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178187/
https://www.ncbi.nlm.nih.gov/pubmed/32230980
http://dx.doi.org/10.3390/ijms21072337

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