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Mining TCGA database for tumor mutation burden and their clinical significance in bladder cancer

Background: Bladder cancer is the ninth most-common cancer worldwide and it is associated with high morbidity and mortality. Tumor mutational burden (TMB) is an emerging biomarker in cancer characterized by microsatellite instability. TMB has been described as a powerful predictor of tumor behavior...

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Detalles Bibliográficos
Autores principales: Lv, Jia, Zhu, Yongze, Ji, Alin, Zhang, Qi, Liao, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178217/
https://www.ncbi.nlm.nih.gov/pubmed/32239176
http://dx.doi.org/10.1042/BSR20194337