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PD-1 IC Inhibition Synergistically Improves Influenza A Virus-Mediated Oncolysis of Metastatic Pulmonary Melanoma

Recently, we showed that infection of primary lung tumor-bearing mice with oncolytic influenza A viruses (IAVs) led to strong virus-induced tumor cell lysis but also to restoration of immune competence of innate immune cells. Murine B16-F10 melanoma cells are known for their high lung tropism and pr...

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Detalles Bibliográficos
Autores principales: Sitnik, Siarhei, Masemann, Dörthe, Leite Dantas, Rafael, Wixler, Viktor, Ludwig, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178321/
https://www.ncbi.nlm.nih.gov/pubmed/32346609
http://dx.doi.org/10.1016/j.omto.2020.03.023