Causal network perturbations for instance-specific analysis of single cell and disease samples

MOTIVATION: Complex diseases involve perturbation in multiple pathways and a major challenge in clinical genomics is characterizing pathway perturbations in individual samples. This can lead to patient-specific identification of the underlying mechanism of disease thereby improving diagnosis and per...

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Detalles Bibliográficos
Autores principales: Buschur, Kristina L, Chikina, Maria, Benos, Panayiotis V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178399/
https://www.ncbi.nlm.nih.gov/pubmed/31873725
http://dx.doi.org/10.1093/bioinformatics/btz949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178399/
https://www.ncbi.nlm.nih.gov/pubmed/31873725
http://dx.doi.org/10.1093/bioinformatics/btz949

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