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Causal network perturbations for instance-specific analysis of single cell and disease samples
MOTIVATION: Complex diseases involve perturbation in multiple pathways and a major challenge in clinical genomics is characterizing pathway perturbations in individual samples. This can lead to patient-specific identification of the underlying mechanism of disease thereby improving diagnosis and per...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178399/ https://www.ncbi.nlm.nih.gov/pubmed/31873725 http://dx.doi.org/10.1093/bioinformatics/btz949 |