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FilTar: using RNA-Seq data to improve microRNA target prediction accuracy in animals

MOTIVATION: MicroRNA (miRNA) target prediction algorithms do not generally consider biological context and therefore generic target prediction based on seed binding can lead to a high level of false-positive predictions. Here, we present FilTar, a method that incorporates RNA-Seq data to make miRNA...

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Detalles Bibliográficos
Autores principales: Bradley, Thomas, Moxon, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178423/
https://www.ncbi.nlm.nih.gov/pubmed/31930382
http://dx.doi.org/10.1093/bioinformatics/btaa007