Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions

xCT forms part of the x(c)(−) cysteine-glutamate antiporter which inhibits antimicrobial inflammatory immune functions and thus increases susceptibility to tuberculosis (TB). However, the associations between xCT gene polymorphisms and susceptibility to TB, as well as whether these modulate xCT expr...

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Detalles Bibliográficos
Autores principales: Wang, Wenfei, Cai, Yi, Deng, Guofang, Yang, Qianting, Tang, Peijun, Wu, Meiying, Yu, Ziqi, Yang, Fan, Chen, Jianyong, Werz, Oliver, Chen, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178550/
https://www.ncbi.nlm.nih.gov/pubmed/32321821
http://dx.doi.org/10.1128/mSphere.00263-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178550/
https://www.ncbi.nlm.nih.gov/pubmed/32321821
http://dx.doi.org/10.1128/mSphere.00263-20

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