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Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions
xCT forms part of the x(c)(−) cysteine-glutamate antiporter which inhibits antimicrobial inflammatory immune functions and thus increases susceptibility to tuberculosis (TB). However, the associations between xCT gene polymorphisms and susceptibility to TB, as well as whether these modulate xCT expr...
Autores principales: | Wang, Wenfei, Cai, Yi, Deng, Guofang, Yang, Qianting, Tang, Peijun, Wu, Meiying, Yu, Ziqi, Yang, Fan, Chen, Jianyong, Werz, Oliver, Chen, Xinchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178550/ https://www.ncbi.nlm.nih.gov/pubmed/32321821 http://dx.doi.org/10.1128/mSphere.00263-20 |
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