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Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells

BACKGROUND: The complexity of the neurovascular unit (NVU) poses a challenge in the investigations of drug transport across the blood–brain barrier (BBB) and the function of the brain capillary endothelium. Several in vitro models of the brain capillary endothelium have been developed. In vitro cult...

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Detalles Bibliográficos
Autores principales: Goldeman, C., Ozgür, B., Brodin, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178567/
https://www.ncbi.nlm.nih.gov/pubmed/32321539
http://dx.doi.org/10.1186/s12987-020-00193-5