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Epigenetic prediction of complex traits and mortality in a cohort of individuals with oropharyngeal cancer

BACKGROUND: DNA methylation (DNAm) variation is an established predictor for several traits. In the context of oropharyngeal cancer (OPC), where 5-year survival is ~ 65%, DNA methylation may act as a prognostic biomarker. We examined the accuracy of DNA methylation biomarkers of 4 complex exposure t...

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Detalles Bibliográficos
Autores principales: Langdon, Ryan J., Beynon, Rhona A., Ingarfield, Kate, Marioni, Riccardo E., McCartney, Daniel L., Martin, Richard M., Ness, Andy R., Pawlita, Michael, Waterboer, Tim, Relton, Caroline, Thomas, Steven J., Richmond, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178612/
https://www.ncbi.nlm.nih.gov/pubmed/32321578
http://dx.doi.org/10.1186/s13148-020-00850-4