ATAC-seq normalization method can significantly affect differential accessibility analysis and interpretation

BACKGROUND: Chromatin dysregulation is associated with developmental disorders and cancer. Numerous methods for measuring genome-wide chromatin accessibility have been developed in the genomic era to interrogate the function of chromatin regulators. A recent technique which has gained widespread use...

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Detalles Bibliográficos
Autores principales: Reske, Jake J., Wilson, Mike R., Chandler, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178746/
https://www.ncbi.nlm.nih.gov/pubmed/32321567
http://dx.doi.org/10.1186/s13072-020-00342-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178746/
https://www.ncbi.nlm.nih.gov/pubmed/32321567
http://dx.doi.org/10.1186/s13072-020-00342-y

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