Targeting the 4-1BB costimulatory molecule through single chain antibodies promotes the human T-cell response

BACKGROUND: Adoptive T-cell therapy (ACT) using autologous tumor-reactive T lymphocytes has considerable potential for cancer immunotherapy. In ACT, T cells are isolated from cancer patients and then stimulated and expanded in vitro by cytokines and costimulatory molecules. 4-1BB is an important cos...

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Detalles Bibliográficos
Autores principales: Bagheri, Salman, Safaie Qamsari, Elmira, Yousefi, Mehdi, Riazi-Rad, Farhad, Sharifzadeh, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178758/
https://www.ncbi.nlm.nih.gov/pubmed/32336974
http://dx.doi.org/10.1186/s11658-020-00219-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178758/
https://www.ncbi.nlm.nih.gov/pubmed/32336974
http://dx.doi.org/10.1186/s11658-020-00219-8

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