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In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes

CONTEXT: Ganoderic acid A (GAA) is usually used to prevent cancers or other diseases, which make it likely to be used with other drugs metabolized by cytochromes P450. OBJECTIVE: This study investigates the effect of GAA on eight major cytochrome P450 isoforms in human liver microsomes. MATERIAL AND...

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Detalles Bibliográficos
Autores principales: Xu, Shangchen, Zhang, Fengqing, Chen, Dali, Su, Keren, Zhang, Li, Jiang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178866/
https://www.ncbi.nlm.nih.gov/pubmed/32285742
http://dx.doi.org/10.1080/13880209.2020.1747500