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Cytology cell blocks from malignant pleural effusion are good candidates for PD-L1 detection in advanced NSCLC compared with matched histology samples

BACKGROUND: Detection of programmed cell death ligand-1 (PD-L1) by immunohistochemistry (IHC) has been commonly used to predict the efficacy of treatment with PD-1/PD-L1 inhibitors. However, there is limited literature regarding the reliability of PD-L1 testing using malignant pleural effusion (MPE)...

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Detalles Bibliográficos
Autores principales: Zou, Yinying, Xu, Liming, Tang, Qiusu, You, Qihan, Wang, Xiaoling, Ding, Wei, Zhao, Jing, Ren, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178995/
https://www.ncbi.nlm.nih.gov/pubmed/32321471
http://dx.doi.org/10.1186/s12885-020-06851-z