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Xiaochaihutang Improves the Cortical Astrocyte Edema in Thioacetamide-Induced Rat Acute Hepatic Encephalopathy by Activating NRF2 Pathway

Oxidative stress induced by high ammonia, which leads to astrocyte edema, is the key to acute hepatic encephalopathy (AHE). Nuclear factor erythroid 2-related factor 2 (NRF2) has been implicated in oxidative stress, but the mechanism of NRF2 against ammonia-induced astrocytes edema has not been full...

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Detalles Bibliográficos
Autores principales: Jia, Weiyi, Liu, Jiajia, Hu, Rui, Hu, Anling, Tang, Weiwei, Li, Lijuan, Li, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179068/
https://www.ncbi.nlm.nih.gov/pubmed/32372950
http://dx.doi.org/10.3389/fphar.2020.00382