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DNA-Binding and Anticancer Activity of Binuclear Gold(I) Alkynyl Complexes with a Phenanthrenyl Bridging Ligand

3,6-Diethynyl-9,10-diethoxyphenanthrene (4) was synthesized from phenanthrene and employed in the synthesis of the binuclear gold(I) alkynyl complexes (R(3)P)Au(C≡C–3-[C(14)H(6)-9,10-diethoxy]-6–C≡C)Au(PR(3)) (R = Ph (5a), Cy (5b)). The diyne 4 and complexes 5a and 5b were characterized by NMR spect...

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Detalles Bibliográficos
Autores principales: Alsaeedi, Mona S., Babgi, Bandar A., Hussien, Mostafa A., Abdellattif, Magda H., Humphrey, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179095/
https://www.ncbi.nlm.nih.gov/pubmed/32106590
http://dx.doi.org/10.3390/molecules25051033