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Design, Synthesis, Computational, and Preclinical Evaluation of (nat)Ti/(45)Ti-Labeled Urea-Based Glutamate PSMA Ligand

Despite promising anti-cancer properties in vitro, all titanium-based pharmaceuticals have failed in vivo. Likewise, no target-specific positron emission tomography (PET) tracer based on the radionuclide (45)Ti has been developed, notwithstanding its excellent PET imaging properties. In this contrib...

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Detalles Bibliográficos
Autores principales: Søborg Pedersen, Kristina, Baun, Christina, Michaelsen Nielsen, Karin, Thisgaard, Helge, Ingemann Jensen, Andreas, Zhuravlev, Fedor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179113/
https://www.ncbi.nlm.nih.gov/pubmed/32131399
http://dx.doi.org/10.3390/molecules25051104