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Design, Synthesis, Computational, and Preclinical Evaluation of (nat)Ti/(45)Ti-Labeled Urea-Based Glutamate PSMA Ligand
Despite promising anti-cancer properties in vitro, all titanium-based pharmaceuticals have failed in vivo. Likewise, no target-specific positron emission tomography (PET) tracer based on the radionuclide (45)Ti has been developed, notwithstanding its excellent PET imaging properties. In this contrib...
Autores principales: | Søborg Pedersen, Kristina, Baun, Christina, Michaelsen Nielsen, Karin, Thisgaard, Helge, Ingemann Jensen, Andreas, Zhuravlev, Fedor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179113/ https://www.ncbi.nlm.nih.gov/pubmed/32131399 http://dx.doi.org/10.3390/molecules25051104 |
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