Cargando…

Mutations in Superoxide Dismutase 1 (Sod1) Linked to Familial Amyotrophic Lateral Sclerosis Can Disrupt High-Affinity Zinc-Binding Promoted by the Copper Chaperone for Sod1 (Ccs)

Zinc (II) ions (hereafter simplified as zinc) are important for the structural and functional activity of many proteins. For Cu, Zn superoxide dismutase (Sod1), zinc stabilizes the native structure of each Sod1 monomer, promotes homo-dimerization and plays an important role in activity by “softening...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boyd, Stefanie D., Ullrich, Morgan S., Calvo, Jenifer S., Behnia, Fatemeh, Meloni, Gabriele, Winkler, Duane D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179120/ https://www.ncbi.nlm.nih.gov/pubmed/32121118 http://dx.doi.org/10.3390/molecules25051086

Ejemplares similares

Quantifying the Interaction between Copper-Zinc Superoxide Dismutase (Sod1) and its Copper Chaperone (Ccs1)
por: Boyd, Stefanie D, et al.
Publicado: (2018)

Copper–zinc superoxide dismutase (Sod1) activation terminates interaction between its copper chaperone (Ccs) and the cytosolic metal-binding domain of the copper importer Ctr1
por: Skopp, Amélie, et al.
Publicado: (2019)

Superoxide Dismutases (SODs) and SOD Mimetics
por: Borgstahl, Gloria E. O., et al.
Publicado: (2018)

Superoxide Dismutase Gene (SOD1, SOD2, and SOD3) Polymorphisms and Antituberculosis Drug-induced Hepatitis
por: Kim, Sang-Hoon, et al.
Publicado: (2015)

Copper Sources for Sod1 Activation
por: Boyd, Stefanie D., et al.
Publicado: (2020)

S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects
por: Antinone, Sarah E., et al.
Publicado: (2017)

A molecular chaperone activity of CCS restores the maturation of SOD1 fALS mutants
por: Luchinat, Enrico, et al.
Publicado: (2017)

Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS
por: Sala, Fernanda A., et al.
Publicado: (2019)

Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis
por: Pereira, Gabriel Rodrigues Coutinho, et al.
Publicado: (2021)

Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1‐Related Amyotrophic Lateral Sclerosis
por: Samanta, Nirnay, et al.
Publicado: (2022)

Analysis of Feeding Behavior Characteristics in the Cu/Zn Superoxide Dismutase 1 (SOD1) SOD1G93A Mice Model for Amyotrophic Lateral Sclerosis (ALS)
por: Kitaoka, Yoshihiro, et al.
Publicado: (2023)

Alterations in Concentration/Activity of Superoxide Dismutases in Context of Obesity and Selected Single Nucleotide Polymorphisms in Genes: SOD1, SOD2, SOD3
por: Lewandowski, Łukasz, et al.
Publicado: (2020)

Superoxide dismutase SOD-1 modulates C. elegans pathogen avoidance behavior
por: Horspool, Alexander M., et al.
Publicado: (2017)

Modification of Superoxide Dismutase 1 (SOD1) Properties by a GFP Tag – Implications for Research into Amyotrophic Lateral Sclerosis (ALS)
por: Stevens, James C., et al.
Publicado: (2010)

The activity of superoxide dismutases (SODs) at the early stages of wheat deetiolation
por: Leonowicz, Gracjana, et al.
Publicado: (2018)

Pyrimethamine significantly lowers cerebrospinal fluid Cu/Zn superoxide dismutase in amyotrophic lateral sclerosis patients with SOD1 mutations
por: Lange, Dale J., et al.
Publicado: (2017)

Superoxide Dismutases, SOD1 and SOD2, Play a Distinct Role in the Fat Body during Pupation in Silkworm Bombyx mori
por: Nojima, Yosui, et al.
Publicado: (2015)

A lecithinized superoxide dismutase (PC-SOD) improves ulcerative colitis
por: Suzuki, Y, et al.
Publicado: (2008)

Human extracellular superoxide dismutase (EC-SOD) expression in transgenic chicken
por: Byun, Sung June, et al.
Publicado: (2013)

The Effect of Extracellular Superoxide Dismutase (SOD3) Gene in Lung Cancer
por: Zhang, Yundi, et al.
Publicado: (2022)

Brain Protease Activated Receptor 1 Pathway: A Therapeutic Target in the Superoxide Dismutase 1 (SOD1) Mouse Model of Amyotrophic Lateral Sclerosis
por: Shavit-Stein, Efrat, et al.
Publicado: (2020)

Ceruloplasmin and superoxide dismutase (SOD1) in heterozygotes for Wilson disease: A case control study
por: Tórsdóttir, Gudlaug, et al.
Publicado: (2009)

Cytosolic Superoxide Dismutase (SOD1) Is Critical for Tolerating the Oxidative Stress of Zinc Deficiency in Yeast
por: Wu, Chang-Yi, et al.
Publicado: (2009)

Conformational dynamics of superoxide dismutase (SOD1) in osmolytes: a molecular dynamics simulation study
por: Jahan, Ishrat, et al.
Publicado: (2020)

Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224)
por: Doñate, F, et al.
Publicado: (2008)

A faulty interaction between SOD1 and hCCS in neurodegenerative disease
por: Wright, Gareth S. A., et al.
Publicado: (2016)

Molecular and pharmacological chaperones for SOD1
por: Wright, Gareth S.A.
Publicado: (2020)

Copper Chaperone for Superoxide Dismutase FoCCS1 in Frankliniella occidentalis May Be Associated with Feeding Adaptation after Host Shifting
por: Zhang, Tao, et al.
Publicado: (2022)

Superoxide Dismutase 1 Nanoparticles (Nano-SOD1) as a Potential Drug for the Treatment of Inflammatory Eye Diseases
por: Vaneev, Alexander N., et al.
Publicado: (2021)

Exogenous C(8)-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells
por: Chang, Yuli C., et al.
Publicado: (2018)

The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulate enzymatic activity
por: Petersen, Steen V, et al.
Publicado: (2007)

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans
por: Van Raamsdonk, Jeremy M., et al.
Publicado: (2009)

A copper chaperone–mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis
por: McAlary, L., et al.
Publicado: (2022)

High-Resolution Melting (HRM) Analysis of the Cu/Zn Superoxide Dismutase (SOD1) Gene in Japanese Sporadic Amyotrophic Lateral Sclerosis (SALS) Patients
por: Akimoto, Chizuru, et al.
Publicado: (2011)

Cloning and high-level expression of monomeric human superoxide dismutase 1 (SOD1) and its interaction with pyrimidine analogs
por: LeVatte, Marcia, et al.
Publicado: (2021)

Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)
por: Gupta, Govind, et al.
Publicado: (2022)

Changes in the Activity and Concentration of Superoxide Dismutase Isoenzymes (Cu/Zn SOD, MnSOD) in the Blood of Healthy Subjects and Patients with Acute Pancreatitis
por: Ściskalska, Milena, et al.
Publicado: (2020)

Radioprotective and tumor antiangiogenic effect of the novel synthetic superoxide dismutase (SOD) mimetic compounds
por: Vujaskovic, Z, et al.
Publicado: (2001)

Formation of High-Order Oligomers by a Hyperthemostable Fe-Superoxide Dismutase (tcSOD)
por: Wang, Sha, et al.
Publicado: (2014)

Immunohistochemical assessment of mitochondrial superoxide dismutase (MnSOD) in colorectal premalignant and malignant lesions
por: Piecuch, Adam, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3fjdnbou0sakek8bqvn05212fp