Characterizations and Assays of α-Glucosidase Inhibition Activity on Gallic Acid Cocrystals: Can the Cocrystals be Defined as a New Chemical Entity During Binding with the α-Glucosidase?

Cocrystallization with co-former (CCF) has proved to be a powerful approach to improve the solubility and even bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). However, it is still uncertain whether a cocrystal would exert the pharmacological activity in the form of...

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Detalles Bibliográficos
Autores principales: Xue, Na, Jia, Yutao, Li, Congwei, He, Binnan, Yang, Caiqin, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179128/
https://www.ncbi.nlm.nih.gov/pubmed/32150882
http://dx.doi.org/10.3390/molecules25051163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179128/
https://www.ncbi.nlm.nih.gov/pubmed/32150882
http://dx.doi.org/10.3390/molecules25051163

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