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Protective Effect of Genistein against Compound 48/80 Induced Anaphylactoid Shock via Inhibiting MAS Related G Protein-Coupled Receptor X2 (MRGPRX2)

Anaphylactoid shock is a fatal hypersensitivity response caused by non-IgE mediated mast cell activation. These reactions are mediated by a family of G protein-coupled receptors (GPCRs) known as Mas related GPCRX2 (MRGPRX2). Several US FDA approved drugs which are used in day to day life have been r...

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Detalles Bibliográficos
Autores principales: Kumar, Mukesh, Singh, Kailash, Duraisamy, Karthi, Allam, Ahmed A., Ajarem, Jamaan, Kwok Chong CHOW, Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179155/
https://www.ncbi.nlm.nih.gov/pubmed/32106575
http://dx.doi.org/10.3390/molecules25051028