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Synthesis and Bioactivity Assessment of Novel Spiro Pyrazole-Oxindole Congeners Exhibiting Potent and Selective in vitro Anticancer Effects

The present work aims to design and synthesize novel series of spiro pyrazole-3,3’-oxindoles analogues and investigate their bioactivity as antioxidant and antimicrobial agents, as well as antiproliferative potency against selected human cancerous cell lines (i.e., breast, MCF-7; colon, HCT-116 and...

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Detalles Bibliográficos
Autores principales: Abo-Salem, Heba M., Nassrallah, Amr, Soliman, Ahmed A.F., Ebied, Manal S., Elawady, Mohamed E., Abdelhamid, Sayeda A., El-Sawy, Eslam R., Al-Sheikh, Yazeed A., Aboul-Soud, Mourad A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179167/
https://www.ncbi.nlm.nih.gov/pubmed/32138244
http://dx.doi.org/10.3390/molecules25051124