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Design and Synthesis of Molecular Hybrids of Sophora Alkaloids and Cinnamic Acids as Potential Antitumor Agents

Twenty-five sophora alkaloids-cinnamic acid hybrids (including matrine-cinnamic acid hybrids, sophoridine-cinnamic acid hybrids, and sophocarpine-cinnamic acid hybrids) were designed, synthesized, and evaluated in vitro against three human tumor cell lines (HeLa, HepG2 and A549) with cisplatin as a...

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Detalles Bibliográficos
Autores principales: Shang, Hai, Li, Lingyu, Ma, Liyan, Tian, Yu, Jia, Hongmei, Zhang, Tao, Yu, Meng, Zou, Zhongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179170/
https://www.ncbi.nlm.nih.gov/pubmed/32150948
http://dx.doi.org/10.3390/molecules25051168