A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies

The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent. The latter are prone to extensive cooperation and like a virtuos...

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Detalles Bibliográficos
Autores principales: Bojarska, Joanna, Remko, Milan, Breza, Martin, Madura, Izabela D., Kaczmarek, Krzysztof, Zabrocki, Janusz, Wolf, Wojciech M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179192/
https://www.ncbi.nlm.nih.gov/pubmed/32138329
http://dx.doi.org/10.3390/molecules25051135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179192/
https://www.ncbi.nlm.nih.gov/pubmed/32138329
http://dx.doi.org/10.3390/molecules25051135

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