Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

Tyrosine kinase inhibitors revolutionized cancer therapy but still evoke strong adverse effects that can dramatically reduce patients’ quality of life. One possibility to enhance drug safety is the exploitation of prodrug strategies to selectively activate a drug inside the tumor tissue. In this stu...

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Detalles Bibliográficos
Autores principales: Bielec, Bjoern, Poetsch, Isabella, Ahmed, Esra, Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179202/
https://www.ncbi.nlm.nih.gov/pubmed/32143435
http://dx.doi.org/10.3390/molecules25051149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179202/
https://www.ncbi.nlm.nih.gov/pubmed/32143435
http://dx.doi.org/10.3390/molecules25051149

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