Synthesis of Tetrabenazine and Its Derivatives, Pursuing Efficiency and Selectivity

Tetrabenazine is a US Food and Drug Administration (FDA)-approved drug that exhibits a dopamine depleting effect and is used for the treatment of chorea in Huntington’s disease. Mechanistically, tetrabenazine binds and inhibits vesicular monoamine transporter type 2, which is responsible for importi...

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Detalles Bibliográficos
Autor principal: Paek, Seung-Mann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179236/
https://www.ncbi.nlm.nih.gov/pubmed/32151010
http://dx.doi.org/10.3390/molecules25051175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179236/
https://www.ncbi.nlm.nih.gov/pubmed/32151010
http://dx.doi.org/10.3390/molecules25051175

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