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Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

Retinal degeneration is a form of neurodegenerative disease and is the leading cause of vision loss globally. The Toll-like receptors (TLRs) are primary components of the innate immune system involved in signal transduction. Here we show that TLR2 induces complement factors C3 and CFB, the common an...

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Detalles Bibliográficos
Autores principales: Mulfaul, Kelly, Ozaki, Ema, Fernando, Nilisha, Brennan, Kiva, Chirco, Kathleen R., Connolly, Emma, Greene, Chris, Maminishkis, Arvydas, Salomon, Robert G., Linetsky, Mikhail, Natoli, Riccardo, Mullins, Robert F., Campbell, Matthew, Doyle, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179253/
https://www.ncbi.nlm.nih.gov/pubmed/32075760
http://dx.doi.org/10.1016/j.celrep.2020.01.064