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Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration
Retinal degeneration is a form of neurodegenerative disease and is the leading cause of vision loss globally. The Toll-like receptors (TLRs) are primary components of the innate immune system involved in signal transduction. Here we show that TLR2 induces complement factors C3 and CFB, the common an...
Autores principales: | Mulfaul, Kelly, Ozaki, Ema, Fernando, Nilisha, Brennan, Kiva, Chirco, Kathleen R., Connolly, Emma, Greene, Chris, Maminishkis, Arvydas, Salomon, Robert G., Linetsky, Mikhail, Natoli, Riccardo, Mullins, Robert F., Campbell, Matthew, Doyle, Sarah L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179253/ https://www.ncbi.nlm.nih.gov/pubmed/32075760 http://dx.doi.org/10.1016/j.celrep.2020.01.064 |
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