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Analgesic and side effects of intravenous recombinant Phα1β

BACKGROUND: Intrathecal injection of voltage-sensitive calcium channel blocker peptide toxins exerts analgesic effect in several animal models of pain. Upon intrathecal administration, recombinant Phα1β exerts the same analgesic effects as the those of the native toxin. However, from a clinical pers...

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Detalles Bibliográficos
Autores principales: Rigo, Flavia Karine, Rossato, Mateus Fortes, Borges, Vanessa, da Silva, Juliana Figueira, Pereira, Elizete Maria Rita, de Ávila, Ricardo Andrez Machado, Trevisan, Gabriela, dos Santos, Duana Carvalho, Diniz, Danuza Montijo, Silva, Marco Aurélio Romano, de Castro, Célio José, Cunha, Thiago Mattar, Ferreira, Juliano, Gomez, Marcus Vinicius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179342/
https://www.ncbi.nlm.nih.gov/pubmed/32362927
http://dx.doi.org/10.1590/1678-9199-JVATITD-2019-0070