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Synthesis of Functionalized Indoles via Palladium-Catalyzed Cyclization of N-(2-allylphenyl) Benzamide: A Method for Synthesis of Indomethacin Precursor

We developed an efficient method for synthesis of substituted N-benzoylindole via Pd(II)-catalyzed C–H functionalization of substituted N-(2-allylphenyl)benzamide. The reaction showed a broad substrate scope (including N-acetyl and N-Ts substrates) and substituted indoles were obtained in good to ex...

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Detalles Bibliográficos
Autores principales: Chang, Zhe, Ma, Tong, Zhang, Yu, Dong, Zheng, Zhao, Heng, Zhao, Depeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179414/
https://www.ncbi.nlm.nih.gov/pubmed/32182955
http://dx.doi.org/10.3390/molecules25051233