Synthesis and Antiproliferative Screening Of Novel Analogs of Regioselectively Demethylated Colchicine and Thiocolchicine

Colchicine, a pseudoalkaloid isolated from Colchicum autumnale, has been identified as a potent anticancer agent because of its strong antimitotic activity. It was shown that colchicine modifications by regioselective demethylation affected its biological properties. For demethylated colchicine anal...

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Detalles Bibliográficos
Autores principales: Czerwonka, Dominika, Sobczak, Szymon, Maj, Ewa, Wietrzyk, Joanna, Katrusiak, Andrzej, Huczyński, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179419/
https://www.ncbi.nlm.nih.gov/pubmed/32151042
http://dx.doi.org/10.3390/molecules25051180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179419/
https://www.ncbi.nlm.nih.gov/pubmed/32151042
http://dx.doi.org/10.3390/molecules25051180

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