Pharmacokinetics of Two Chlorine-Substituted Bis-Pyridinium Mono-Aldoximes with Regenerating Effect on Butyrylcholinesterase

Our aim was to find chlorine-substituted antidotes against organophosphate poisoning and compare their pharmacokinetics to their parent compound, K-203. White male Wistar rats were intramuscularly injected with K-203, K-867 or K-870. Serum, brain, kidneys, liver, lung, eyes, and testes tissues were...

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Detalles Bibliográficos
Autores principales: Kalász, Huba, Szimrók, Zoltán, Karvaly, Gellért, Adeghate, Jennifer, Tekes, Kornélia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179459/
https://www.ncbi.nlm.nih.gov/pubmed/32164301
http://dx.doi.org/10.3390/molecules25051250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179459/
https://www.ncbi.nlm.nih.gov/pubmed/32164301
http://dx.doi.org/10.3390/molecules25051250

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