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Ischemia Enhances the Acute Stretch-Induced Increase in Calcium Spark Rate in Ventricular Myocytes
Introduction: In ventricular myocytes, spontaneous release of calcium (Ca(2+)) from the sarcoplasmic reticulum via ryanodine receptors (“Ca(2+) sparks”) is acutely increased by stretch, due to a stretch-induced increase of reactive oxygen species (ROS). In acute regional ischemia there is stretch of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179564/ https://www.ncbi.nlm.nih.gov/pubmed/32372969 http://dx.doi.org/10.3389/fphys.2020.00289 |