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Ischemia Enhances the Acute Stretch-Induced Increase in Calcium Spark Rate in Ventricular Myocytes

Introduction: In ventricular myocytes, spontaneous release of calcium (Ca(2+)) from the sarcoplasmic reticulum via ryanodine receptors (“Ca(2+) sparks”) is acutely increased by stretch, due to a stretch-induced increase of reactive oxygen species (ROS). In acute regional ischemia there is stretch of...

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Detalles Bibliográficos
Autores principales: Cameron, Breanne A., Kai, Hiroaki, Kaihara, Keiko, Iribe, Gentaro, Quinn, T. Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179564/
https://www.ncbi.nlm.nih.gov/pubmed/32372969
http://dx.doi.org/10.3389/fphys.2020.00289